Illness

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Illness

Parkinson's

Parkinson’s, a fear not only about shaking

Parkinson’s is considered to be in the group of dementia. In Thai people, the occurrence of Parkinson’s is ranked second only to Alzheimer’s. According to the statistics, this disease is often found in people age 60 years old and above. It occurs in males more than females by 50% or 1.5 times.

Why does this disease have the symptoms of shaking and contractions?

These symptoms are often caused by the degeneration of the midbrain, called Substantia Nigra, which is the center of nerve cells that produce Dopamine. Dopamine is a neurotransmitter that helps to increase the transmission of nerve impulses, allowing you to move limb muscles quickly as desired.


However, this part of the brain in patients with Parkinson’s has degenerated. The Dopamine in the brain is not enough to take the nerve impulses to other muscles. Therefore, patients cannot move their body freely as desired. As a consequence, the external symptoms are shaking while walking, hand shaking, writing in small letters, shaking and disorganized line pattern, stammering, slow movement, staggering, loss of balance, and eventually the bedridden phase.



Causes of degenerative Substantia Nigra

1. Those with people in the family with Parkinson’s. The direct family members have a chance of having this disease more than ordinary people.

2. The accumulation of toxins and chemicals, such as insecticides, food preservatives, and heavy metal toxins.

3. Degeneration of blood vessels that reduce the blood circulation rate to the brain.

4. Types of food and consumption. It is found that flour, sugar, desserts, and fried food can increase the inflammation process in the nervous system.

5. Imbalance of microorganisms in the digestive tract. From current studies, the microorganisms in the digestive tract are related with the synthesis of neurotransmitters, immune system, and gene control from the genetic line.

6. Defective autophagy, which causes the accumulation of protein sludge in this part of the brain cell, or what is called Lewy bodies, that faster degenerate this part of the brain.



What is the shaking like? How do we know if we have “Parkinson’s”?

The diagnosis of Parkinson’s uses the symptom diagnosis principle, which mainly comes from asking for information and examining the body together with blood testing or CT scan or MRI of the brain to distinguish diseases of the central nervous system with others.


With current technology, there is the examination of the brain function, which is called Functional MRI, like F-Dopa Pet Scan which  can measure an abnormality of Dopamine in the brain of patients with Parkinson’s.


The treatment of Parkinson’s at present emphasizes using medication that can reduce the destruction of Dopamine to maintain the level of Dopamine. It is found that the use of medication for the treatment provides good effect in controlling food for better movement. In the first phase, do not forget that degeneration of the brain is not corrected and may gradually increase. Therefore, in the long run, the doses must be gradually increased until the body has complications from the medication, such as psychiatric symptoms, hallucination, depression, and obsessive compulsive disorder.


Even though there are technologies to manage the medication to maintain the level of Dopamine now, which is brain stimulation surgery to increase the secretion of Dopamine, continuous drug management technique through the skin or the intestine might help to reduce the disturbance of Dopamine levels and may reduce the side effects. However, it is not a treatment of the cause, to withhold or slow down the degeneration that might occur inside the brain.



Integrative treatment guideline, a new hope for Parkinson’s treatment

By using the treatment guidelines that are able to control all factors to reduce the rate of degenerative brain cells, which are:


1. Therapy by detoxifying heavy metal toxins from the body to reduce the accumulation of toxins, such as lead, manganese, or excessive iron that can increasingly destroy the Substantia Nigra.


2. Intermittent Fasting is a natural therapy technique by reducing the consumption of dinner and changing to drinking freshly squeezed vegetable juice, which can stimulate the genes in the body to increase the function of the autophagy mechanism.


3. Immune therapy technology to adjust the balance of immunity and control the inflammation process in the body, which can slow down the degeneration of the central nervous system.


4. The use of nutrient therapy, such as vitamins, minerals, and essential fatty acids, including antioxidants, like Coenzyme Q10, Alpha Lipoic Acid, ginseng and cordycep extract, and green tea leaf extract, such as EGCG that helps to adjust the balance of neurotransmitters and reduce the rate of degenerative brain cells.


5. Stimulate the brain cell by using low level near infrared laser therapy. It was found that infrared can stimulate cytochrome C enzyme of Mitochondria of the nerve cell, which affects the function of degenerative cells to become better.


6. The use of biomolecule therapy, such as Cerebrolysin or cell therapy. There are case studies that show it tends to provide good results for increasing degenerative brain cell repair for diseases such as Parkinson’s or Alzheimer’s, which is considered to be an interesting alternative treatment and hope for this group of patients in the future.


For all treatments, we are dedicated to considering individual treatment for each person that treats the source of the problem, that doesn’t only provide treatment by name of symptom or disease. We believe that the best treatment starts from taking care of the patients’ body to have maximum efficacy in recovering themselves.




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